Our succes in integrating information into models that generate unique insights, allowing executives to make better drug development decisions, is reflected in our gold-standard research publications.
Latest publications
Exposure-response relationships of mirvetuximab soravtansine in patients with folate receptor-alpha-positive ovarian cancer: Justification of therapeutic dose regimen | Oncology
Tu YP
, Lagraauw HM
|
qP contributors: Lagraauw HM, Hanze E |
2025|
Journal|
British Journal of Clinical Pharmacology
Link
Population pharmacokinetics and exposure-response relationships of dostarlimab in primary advanced or recurrent endometrial cancer in part 1 of RUBY | Oncology
Kuchimanchi M
, Jorgensen TL
|
qP contributors: Hanze E, Alskar O |
2025|
Journal|
British Journal of Clinical Pharmacology
Link
Population pharmacokinetics of mirvetuximab soravtansine in patients with folate receptor-α positive ovarian cancer: The antibody-drug conjugate, payload and metabolite | Oncology
Tu YP
, Hanze E
|
qP contributors: Hanze E, Lagraauw HM |
2024|
Journal|
British Journal of Clinical Pharmacology
Link
A population pharmacokinetics model of balovaptan to support dose selection in adult and pediatric populations | Pediatrics
Schaedeli Stark F
, Chavanne C
|
qP contributors: Jolling K, Lagraauw HM, Lindbom L, Prins K |
2024|
Journal|
Journal of Pharmacokinetics and Pharmacodynamics
Link
Mechanism-Based Modeling of Perioperative Variations in Hemoglobin Concentration in Patients Undergoing Laparoscopic Surgery | Hematology
Jaramillo S
, Marco-Arino N
|
qP contributors: Marco-Arino N |
2024|
Journal|
Anesthesia & Analgesia
Link
A bispecific antibody approach for the potential prophylactic treatment of inherited bleeding disorders | Haematology
Gandhi P.S
, Zivkovic M
|
qP contributors: Alskar O |
2024|
Journal|
Nature Cardiovascular Research
Link
Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N-dimethyltryptamine benzoate) in healthy participants | CNS
Rucker JJ
, Roberts C
|
qP contributors: Suttle B |
2024|
Journal|
Journal of Psychopharmacology
Link
Personalized Dosing of Medicines for Children: A Primer on Pediatric Pharmacometrics for Clinicians | Pediatrics
Modeling and Simulations in Latin-American Generic Markets: Perspectives from Chilean Local Industry, Regulatory Agency, and Academia | All
A Phase I Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Liposomal Bupivacaine for Sciatic Nerve Block in the Popliteal Fossa for Bunionectomy | Analgesia
Sessler DI
, Bao X
|
qP contributors: Voelkner A |
2024|
Journal|
Journal of Clinical Pharmacology
Link